High Risk

Low Risk

Are You at Risk for
Opioid Addiction?

Opioid medications like oxycodone and hydrocodone are effective for managing pain. But for some people, they bring an increased risk of addiction. Which people? Some of the answer is found in our DNA.

In fact, the genes you carry are an important factor that influences whether you are at high or low risk for opioid addiction (also called Opioid Use Disorder, or OUD).1

Until now, neither patients nor healthcare providers have had a way to understand who may be at increased genetic risk for OUD.

1 Bevilacqua L, Goldman D. Genes and addictions. Clin Pharmacol Ther. 2009; 85(4):359–361. doi:10.1038/clpt.2009.6

AvertD Logo

Designed to Inform

AvertD™ is a simple genetic test that requires only a cheek swab. It analyzes DNA markers associated with opioid addiction and tells you if your risk is high or low. Having this personalized information allows you and your doctor to make more informed decisions about whether the use of oral prescription opioids to manage acute pain is right for you.

If you are identified as having a High Genetic Risk, you and your doctor may wish to explore alternative pain management options in order to minimize or avoid use of opioids. A High Genetic Risk result does not mean you have or will develop OUD, but your risk of developing OUD is ~16 times higher than individuals with a Low Genetic Risk.

If you are identified as having a Low Genetic Risk, you and your doctor should still follow existing guidelines to ensure safe and effective opioid prescribing. A Low Genetic Risk result does not mean you do not have or will not develop OUD, but your risk of developing OUD is ~16 times lower than individuals with a High Genetic Risk.

Because genetics are only one factor in understanding the risk of developing OUD from using oral opioids, AvertD test results should be used in conjunction with a complete clinical evaluation to determine the appropriateness of oral opioids in a pain management plan.

Easy to Use



Before you receive a prescription for oral opioids, ask your healthcare provider to order the AvertD test.



Your provider will receive your results online after your sample arrives at the lab and is processed.



Talk with your provider about what your results mean for your pain management options.


Your Privacy is Important

We respect your privacy and appreciate the trust you have placed in us. Our lab is CAP-accredited and CLIA-certified and follows stringent medical privacy policies and practices. We adhere to the safe and secure storage of all personal health information in a way that is fully compliant with federal government regulations of the Health Information Portability and Accountability Act (HIPAA).

What it Costs

Our goal is to offer the lowest cost option available to you. We are working diligently to ensure AvertD is covered by most insurance companies. Depending on your insurance, your maximum out-of-pocket cost may vary. If coverage is denied or only part of the test is covered, SOLVD Health may appeal the decision on your behalf. Please check with your insurance company to determine coverage. If your insurance does not pay for the test, you will be billed directly for $199.

AvertD Opioid Test

Request the Test

If you’re interested in the AvertD test, let your healthcare provider know. The test results can be used by you and your provider to decide whether opioid pain medications are an appropriate option for you. If they are not, you and your provider can explore other options.

Send us your provider’s contact information by filling out this form, and we’ll contact him or her on your behalf with information about the AvertD test. You can also download this letter, print it, and give it to your doctor at your next appointment.